Sptssb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sptssb
serine palmitoyltransferase, small subunit B
MGI:1913433

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sptssb^{tm1b(KOMP)Mbp}/Sptssb^{tm1b(KOMP)Mbp} C57BL/6N-Sptssb^{tm1b(KOMP)Mbp}/J	abnormal coat appearance	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating iron level	J:211773
	decreased fasting circulating glucose level	J:211773
	increased blood urea nitrogen level	J:211773
	increased fasting circulating glucose level	J:211773
	increased heart weight	J:211773
Sptssb^Tvrm122/Sptssb⁺ involves: A * C57BL/6	abnormal ocular fundus morphology	J:224971
	abnormal retina morphology	J:224971
	brain vacuoles	J:224971
Sptssb^Tvrm122/Sptssb^Tvrm122 involves: A * C57BL/6	abnormal cerebellum white matter morphology	J:224971
	abnormal endoplasmic reticulum stress	J:224971
	abnormal lipid homeostasis	J:224971
	abnormal ocular fundus morphology	J:224971
	abnormal retina inner plexiform layer morphology	J:224971
	abnormal retina outer plexiform layer morphology	J:224971
	ataxia	J:224971
	axon degeneration	J:224971
	brain vacuoles	J:224971
	decreased body weight	J:224971
	optic nerve degeneration	J:224971
	premature death	J:224971

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23