Gprc5a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gprc5a
G protein-coupled receptor, family C, group 5, member A
MGI:1891250

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gprc5a^em1Jaap/Gprc5a^em1Jaap FVB-Gprc5a^em1Jaap	albuminuria	J:293292
	expanded mesangial matrix	J:293292
	glomerulosclerosis	J:293292
	normal growth/size/body region phenotype	J:293292
	normal homeostasis/metabolism phenotype	J:293292
	increased renal glomerulus basement membrane thickness	J:293292
	normal mortality/aging	J:293292
	podocyte foot process effacement	J:293292
	normal renal/urinary system phenotype	J:293292
Gprc5a^tm1Jsx/Gprc5a^tm1Jsx involves: 129X1/SvJ	no abnormal phenotype detected	J:97487
Gprc5a^tm1Rlo/Gprc5a⁺ involves: 129 * C57BL/6	increased lung tumor incidence	J:127821
Gprc5a^tm1Rlo/Gprc5a^tm1Rlo involves: 129 * C57BL/6	increased lung adenocarcinoma incidence	J:127821
	increased lung adenoma incidence	J:127821
	increased lung tumor incidence	J:127821
	lung inflammation	J:127821

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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