Sphk2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sphk2
sphingosine kinase 2
MGI:1861380

6 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sphk2^{Gt(NPX039)Byg}/Sphk2^{Gt(NPX039)Byg} involves: 129P2/OlaHsd * C57BL/6	decreased physiological sensitivity to xenobiotic	J:102911
	normal immune system phenotype	J:102911
Sphk2^tm1.1Stlp/Sphk2^tm1.1Stlp involves: BALB/c	abnormal CD4-positive, alpha-beta T cell physiology	J:153014
Sphk2^tm1Npa/Sphk2^tm1Npa BALB/c-Sphk2^tm1Npa	abnormal B cell physiology	J:129314
Sphk2^tm1Npa/Sphk2^tm1Npa BALB/c-Sphk2^tm1Npa	increased B cell number	J:129314
Sphk2^tm1Rlp/Sphk2^tm1Rlp involves: 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:103755

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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