Clec4e Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Clec4e
C-type lectin domain family 4, member e
MGI:1861232

23 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Clec4e^tm1.1Cfg/Clec4e^tm1.1Cfg B6.Cg-Clec4e^tm1.1Cfg	abnormal heart morphology	J:136334
	abnormal heart valve morphology	J:136334
	abnormal macrophage physiology	J:136334
	decreased lymphocyte cell number	J:136334
	decreased monocyte cell number	J:136334
	decreased neutrophil cell number	J:136334
	decreased tumor necrosis factor secretion	J:136334
	increased susceptibility to fungal infection	J:136334
Clec4e^tm1Tks/Clec4e^tm1Tks involves: 129S1/Sv * 129X1/SvJ	abnormal chemokine secretion	J:203159
	abnormal immune serum protein physiology	J:203159
	abnormal interferon-gamma secretion	J:203159
	abnormal interleukin-17 secretion	J:203159
	abnormal response to infection	J:203159
	decreased circulating interleukin-17 level	J:203159
	decreased dendritic cell number	J:203159
	decreased IgG level	J:203159
	decreased physiological sensitivity to xenobiotic	J:203159
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:203159
	decreased susceptibility to type IV hypersensitivity reaction	J:203159
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:203159
	decreased tumor necrosis factor secretion	J:203159
Clec4e^tm1Tks/Clec4e^tm1Tks involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal chemokine secretion	J:172959
	decreased interleukin-6 secretion	J:172959
	decreased interleukin-10 secretion	J:172959
	decreased neutrophil cell number	J:172959
	decreased susceptibility to fungal infection	J:172959
	decreased tumor necrosis factor secretion	J:172959

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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