Extl3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Extl3
exostosin-like glycosyltransferase 3
MGI:1860765

22 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Extl3^em1(IMPC)Mbp/Extl3⁺ C57BL/6N-Extl3^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal prostate gland morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	enlarged liver	J:211773
	enlarged spleen	J:211773
	microphthalmia	J:211773
	small kidney	J:211773
	small testis	J:211773
Extl3^em1(IMPC)Mbp/Extl3^em1(IMPC)Mbp C57BL/6N-Extl3^em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Extl3^tm1.1Okam/Extl3^tm1.1Okam involves: 129P2/OlaHsd * ICR	embryonic lethality, complete penetrance	J:148348
Extl3^tm1.1Okam/Extl3^tm1Okam Tg(Ins2-cre)#Okam/0 involves: 129P2/OlaHsd * ICR	decreased cell proliferation	J:148348
	decreased circulating insulin level	J:148348
	decreased insulin secretion	J:148348
	decreased pancreatic beta cell mass	J:148348
	decreased pancreatic beta cell number	J:148348
	disorganized pancreatic islets	J:148348
	impaired glucose tolerance	J:148348

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23