Crtam Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crtam
cytotoxic and regulatory T cell molecule
MGI:1859822

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crtam^tm1Achn/Crtam^tm1Achn involves: 129 * C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:145314
	abnormal interleukin secretion	J:145314
	abnormal T cell activation	J:145314
	abnormal T-helper 1 physiology	J:145314
	decreased interferon-gamma secretion	J:145314
	decreased interleukin-17 secretion	J:145314
	increased CD4-positive, alpha-beta T cell number	J:145314
	increased CD8-positive, alpha-beta T cell number	J:145314
	increased susceptibility to bacterial infection	J:145314
	increased T cell proliferation	J:145314
Crtam^tm1Tks/Crtam^tm1Tks B6.Cg-Crtam^tm1Tks	abnormal response to infection	J:152770
Crtam^tm1Tks/Crtam^tm1Tks B6.Cg-Crtam^tm1Tks	normal immune system phenotype	J:152770

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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