Acrbp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acrbp
proacrosin binding protein
MGI:1859515

23 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acrbp^tm1Tba/Acrbp^tm1Tba involves: 129S2/SvPas * ICR	abnormal acrosome assembly	J:234286
	abnormal acrosome morphology	J:234286
	abnormal sperm midpiece morphology	J:234286
	abnormal sperm motility	J:234286, J:294381
	abnormal sperm nucleus morphology	J:234286
	abnormal sperm-egg fusion	J:234286
	abnormal spermiogenesis	J:234286
	asthenozoospermia	J:234286, J:294381
	decreased fertilization frequency	J:234286
	decreased hyperactivated sperm motility	J:234286
	decreased litter size	J:234286
	decreased sperm progressive motility	J:234286, J:294381
	globozoospermia	J:234286
	immotile sperm	J:234286
	impaired binding of sperm to zona pellucida	J:234286
	impaired sperm migration in female genital tract	J:294381
	male infertility	J:234286
	reduced male fertility	J:234286
	normal reproductive system phenotype	J:234286
Acrbp^tm1Tba/Acrbp^tm1Tba Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0 involves: 129S2/SvPas * C57BL/6 * DBA/2 * ICR	impaired acrosome reaction	J:294381
	impaired fertilization	J:294381
	impaired sperm migration in female genital tract	J:294381
	impaired sperm-egg recognition	J:294381
Acrbp^tm1Wen/Acrbp^tm1Wen either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	delayed fertilization	J:102079
	impaired fertilization	J:102079

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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