Irf7 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irf7
interferon regulatory factor 7
MGI:1859212

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Irf3^tm1Ttg/Irf3^tm1Ttg Irf7^tm1Ttg/Irf7^tm1Ttg involves: 129P2/OlaHsd * 129S/SvEv	decreased interferon-beta secretion	J:158969
	decreased interleukin-1 beta secretion	J:158969
	increased susceptibility to bacterial infection	J:158969
	increased susceptibility to Herpesvirales infection	J:158969
	increased susceptibility to Paramyxoviridae infection	J:158969

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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