Icos Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Icos
inducible T cell co-stimulator
MGI:1858745

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd86^tm2Shr/Cd86^tm2Shr Icos^tm1Flv/Icos^tm1Flv involves: 129S1/Sv * 129S4/SvJaeSor	abnormal cytokine level	J:112600
Icos^tm1Flv/Icos^tm1Flv Rc3h1^san/Rc3h1⁺ involves: 129S1/Sv * C57BL/6 * C57BL/6JSfdAnu	decreased lymphoma incidence	J:189087
	increased T cell derived lymphoma incidence	J:189087
Icos^tm1Flv/Icos^tm1Flv Tg(Cd4-Maf)6666Glm/0 involves: 129S1/Sv * C57BL/6	abnormal cytokine secretion	J:112600
Icos^tm1Flv/Icos^tm1Flv Tg(TcraTcrb)425Cbn/0 involves: 129S1/Sv * C57BL/6	abnormal cytokine secretion	J:112600

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24