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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Olig1
oligodendrocyte transcription factor 1
MGI:1355334
31 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Chd7tm1.1Dmm/\Chd7tm1.1Dmm
\Olig1tm1(cre)Rth/\Olig1+
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		decreased myelin sheath thickness J:234565
decreased oligodendrocyte number J:234565
dysmyelination J:234565
\Ezh2tm2Sho/\Ezh2tm2Sho
\Olig1tm1(cre)Rth/0
involves: 129S1/Sv * 129S4/SvJae 		abnormal oligodendrocyte morphology J:256017
dysmyelination J:256017
\Gt(ROSA)26Sortm1(DTA)Mrc/\Gt(ROSA)26Sor+
\Olig1tm1(cre)Rth/\Olig1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		absent oligodendrocytes J:105927
decreased motor neuron number J:105927
lethality throughout fetal growth and development, complete penetrance J:105927
\Ncstntm1.1Sud/\Ncstntm1.1Sud
\Olig1tm1(cre)Rth/\Olig1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal coat appearance J:234705
decreased myelin sheath thickness J:234705
decreased prepulse inhibition J:234705
dysmyelination J:234705
hyperactivity J:234705
increased exploration in new environment J:234705
increased grooming behavior J:234705
increased stereotypic behavior J:234705
skin lesions J:234705
\Olig1tm1(cre)Rth/\Olig1+
\Secisbp2ltm1.1Qiu/\Secisbp2ltm1.1Qiu
involves: 129S4/SvJaeSor * C57BL/6 		abnormal oligodendrocyte differentiation J:333465
decreased myelin sheath thickness J:333465
decreased oligodendrocyte number J:333465
decreased triiodothyronine level J:333465
increased thyroxine level J:333465
tremors J:333465
\Olig1tm1(cre)Rth/\Olig1tm1(cre)Rth
\Dlx1tm1Rth/\Dlx1+
\Dlx2tm1.1Rth/\Dlx2+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		normal mortality/aging J:212992
normal nervous system phenotype J:212992
\Olig1tm1(cre)Rth/\Olig1tm1(cre)Rth
\Dlx1tm1Rth/\Dlx1tm1Rth
\Dlx2tm1.1Rth/\Dlx2tm1.1Rth
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		neonatal lethality, incomplete penetrance J:212992
postnatal lethality, complete penetrance J:212992
\Olig1tm1And/\Olig1tm1And
\Olig2tm1And/\Olig2tm1And
involves: 129 * C57BL/6J 		abnormal nervous system development J:76446
abnormal ventral interneuron 2 morphology J:76446
absent oligodendrocytes J:76446
decreased fetal size J:76446
decreased motor neuron number J:76446
decreased oligodendrocyte progenitor number J:76446
perinatal lethality, complete penetrance J:76446
\Olig1tm1And/\Olig1tm1And
\Olig2tm1And/\Olig2tm1And
\Tg(Olig2)#Wdr/?
Not Specified 		abnormal oligodendrocyte morphology J:210099
\Seh1ltm1Lzha/\Seh1ltm1Lzha
\Olig1tm1(cre)Rth/\Olig1+
involves: 129S4/SvJae * C57BL/6 		abnormal brain development J:276253
abnormal cell differentiation J:276253
ataxia J:276253
decreased oligodendrocyte number J:276253
dysmyelination J:276253
postnatal lethality, complete penetrance J:276253
seizures J:276253
tremors J:276253
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory