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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Olig2
oligodendrocyte transcription factor 2
MGI:1355331
26 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Emx1tm1(cre)Ito/Emx1+
Olig2tm1Qrlu/Olig2tm1Qrlu
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
abnormal myelination J:105071
Olig2tm1(cre/Esr1*)Htak/Olig2tm1(cre/Esr1*)Htak
involves: BALB/c * C57BL/6 * C57BL/6NCrj * CBA
abnormal neuronal migration J:77821
abnormal posture J:77821
abnormal reflex J:77821
abnormal spinal cord morphology J:77821
abnormal spinal cord ventral horn morphology J:77821
aphagia J:77821
decreased motor neuron number J:77821
decreased oligodendrocyte progenitor number J:77821
hypotonia J:77821
neonatal lethality, complete penetrance J:77821
Olig2tm1(cre/Esr1*)Htak/Olig2tm1(cre/Esr1*)Htak
involves: C57BL/6NCrlj * CBA/JNCrlj
abnormal cell differentiation J:203419
abnormal dorsal root ganglion morphology J:182750
abnormal proprioceptive neuron morphology J:182750
abnormal sensory neuron innervation pattern J:182750
abnormal sensory neuron morphology J:182750
decreased motor neuron number J:182750
normal nervous system phenotype J:182750
Olig2tm1Qrlu/Olig2tm1Qrlu
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
abnormal myelination J:105071
Olig2tm1Qrlu/Olig2tm1Qrlu
Tg(GFAP-cre)25Mes/?
involves: 129S4/SvJae * C57BL/6J * FVB/N
abnormal corpus callosum morphology J:105071
abnormal oligodendrocyte morphology J:105071
limb grasping J:105071
tremors J:105071
Olig2tm1Rth/Olig2tm1Rth
involves: 129S4/SvJae * C57BL/6J
abnormal breathing pattern J:75868
abnormal hindbrain development J:75868
abnormal ventral interneuron 2 morphology J:75868
decreased motor neuron number J:75868
decreased oligodendrocyte progenitor number J:75868
no spontaneous movement J:75868
preweaning lethality, complete penetrance J:75868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory