Ddb2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddb2
damage specific DNA binding protein 2
MGI:1355314

7 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ddb2^tm1Linn/Ddb2⁺ involves: 129S/SvEv * C57BL/6	increased incidence of tumors by UV-induction	J:88125
Ddb2^tm1Linn/Ddb2⁺ involves: 129S/SvEv * C57BL/6	increased sensitivity to skin irradiation	J:88125
Ddb2^tm1Linn/Ddb2^tm1Linn involves: 129S/SvEv * C57BL/6	decreased body size	J:88125
	decreased cellular sensitivity to ionizing radiation	J:88125
	increased incidence of tumors by UV-induction	J:88125
	increased sensitivity to skin irradiation	J:88125
Ddb2^tm1Pra/Ddb2⁺ involves: C57BL/6	increased tumor incidence	J:95633
Ddb2^tm1Pra/Ddb2⁺ involves: C57BL/6	premature death	J:95633
Ddb2^tm1Pra/Ddb2^tm1Pra involves: C57BL/6	increased tumor incidence	J:95633
Ddb2^tm1Pra/Ddb2^tm1Pra involves: C57BL/6	premature death	J:95633
Ddb2^tm1Vri/Ddb2⁺ involves: 129P2/Ola * SKH1	increased squamous cell carcinoma incidence	J:103406
Ddb2^tm1Vri/Ddb2^tm1Vri involves: 129P2/Ola	increased sensitivity to skin irradiation	J:103406
Ddb2^tm1Vri/Ddb2^tm1Vri involves: 129P2/Ola * SKH1	increased sensitivity to skin irradiation	J:120007
Ddb2^tm1Vri/Ddb2^tm1Vri involves: 129P2/Ola * SKH1	increased squamous cell carcinoma incidence	J:103406

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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