Polg2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Polg2
polymerase (DNA directed), gamma 2, accessory subunit
MGI:1354947

11 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polg2^M1Rvt/Polg2⁺ involves: BALB/c * C3H/HeH	normal homeostasis/metabolism phenotype	J:277879
	nephrocalcinosis	J:277879
	normal vision/eye phenotype	J:277879
Polg2^tm1.1Wcc/Polg2^tm1.1Wcc involves: C57BL/6 * CBA	abnormal mitochondrial morphology	J:192568
	abnormal respiratory electron transport chain	J:192568
	decreased mitochondrial DNA content	J:192568
	disorganized mitochondrial cristae	J:192568
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:192568
	failure of initiation of embryo turning	J:192568
Polg2^{tm1a(EUCOMM)Wtsi}/Polg2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Polg2^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Polg2^tm1Wcc/Polg2^tm1Wcc Not Specified	no abnormal phenotype detected	J:192568

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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