Mapk6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mapk6
mitogen-activated protein kinase 6
MGI:1354946

32 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mapk6^em1(IMPC)Mbp/Mapk6⁺ C57BL/6N-Mapk6^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal vitreous body morphology	J:211773
	anophthalmia	J:211773
	cataract	J:211773
	decreased body length	J:211773
	decreased brain size	J:211773
	increased startle reflex	J:211773
	no spontaneous movement	J:211773
Mapk6^em1(IMPC)Mbp/Mapk6^em1(IMPC)Mbp C57BL/6N-Mapk6^em1(IMPC)Mbp/MbpMmucd	edema	J:211773
	male infertility	J:211773
	no spontaneous movement	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Mapk6^tm1Melo/Mapk6⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased birth weight	J:153218
Mapk6^tm1Melo/Mapk6^tm1Melo involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal lung development	J:153218
	abnormal lung saccule morphology	J:153218
	abnormal suckling reflex	J:153218
	abnormal type II pneumocyte morphology	J:153218
	abnormal vocalization	J:153218
	atelectasis	J:153218
	carpoptosis	J:153218
	cyanosis	J:153218
	decreased fetal weight	J:153218
	decreased heart weight	J:153218
	decreased liver weight	J:153218
	decreased lung weight	J:153218
	impaired coordination	J:153218
	kyphosis	J:153218
	neonatal lethality, complete penetrance	J:153218
	pulmonary hypoplasia	J:153218
	respiratory distress	J:153218
	respiratory failure	J:153218
	unresponsive to tactile stimuli	J:153218

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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