Orc3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Orc3
origin recognition complex, subunit 3
MGI:1354944

6 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Orc3^tm1.1Zhua/Orc3^tm1.1Zhua Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas	abnormal radial glial cell morphology	J:170581
	decreased neuronal precursor proliferation	J:170581
	decreased radial glial cell number	J:170581
	normal nervous system phenotype	J:170581
Orc3^{tm1a(EUCOMM)Wtsi}/Orc3⁺ C57BL/6N-Orc3^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal pelvic girdle bone morphology	J:211773
Orc3^{tm1a(EUCOMM)Wtsi}/Orc3^{tm1a(EUCOMM)Wtsi} C57BL/6N-Orc3^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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