Kdm2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kdm2b
lysine (K)-specific demethylase 2B
MGI:1354737

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kdm2b^{Gt(RRT043)Byg}/Kdm2b^{Gt(RRT043)Byg} B6.129P2-Kdm2b^{Gt(RRT043)Byg}	abnormal heart morphology	J:231788
	abnormal somite development	J:231788
	decreased embryo size	J:231788
	embryonic lethality during organogenesis, complete penetrance	J:231788, J:233372
	kinked neural tube	J:231788, J:233372
	open neural tube	J:231788
Kdm2b^tm1Nobu/Kdm2b^tm1Nobu either: (involves: 129S/SvEv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J)	abnormal neuronal precursor proliferation	J:171291
	abnormal optic fissure closure	J:171291
	abnormal retina morphology	J:171291
	absent cerebral aqueduct	J:171291
	absent fourth ventricle	J:171291
	curly tail	J:171291
	decreased body size	J:171291
	decreased fetal size	J:171291
	exencephaly	J:171291
	incomplete rostral neuropore closure	J:171291
	increased embryonic neuroepithelium apoptosis	J:171291
	increased head mesenchyme apoptosis	J:171291
	increased hindbrain size	J:171291
	increased midbrain size	J:171291
	intracranial hemorrhage	J:171291
	lethality throughout fetal growth and development, incomplete penetrance	J:171291
	oligozoospermia	J:171291
	open neural tube	J:171291
	preweaning lethality, incomplete penetrance	J:171291
	retina coloboma	J:171291

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