Thop1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Thop1
thimet oligopeptidase 1
MGI:1354165

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Thop1^em1(IMPC)Mbp/Thop1^em1(IMPC)Mbp C57BL/6NCrl-Thop1^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased leukocyte cell number	J:211773
	enlarged seminal vesicle	J:211773
	enlarged spleen	J:211773
	persistence of hyaloid vascular system	J:211773
	small kidney	J:211773
Thop1^{Gt(CSG163)Byg}/Thop1^{Gt(CSG163)Byg} B6.129P2-Thop1^{Gt(CSG163)Byg}	abnormal depression-related behavior	J:290567
	abnormal nervous system physiology	J:290567
	normal behavior/neurological phenotype	J:290567
	decreased lymphocyte cell number	J:290567
	decreased prepulse inhibition	J:290567
	decreased susceptibility to infection	J:290567
	decreased susceptibility to infection induced morbidity/mortality	J:290567
	decreased thermal nociceptive threshold	J:290567
	impaired passive avoidance behavior	J:290567
	increased bleeding time	J:290567
	increased granulocyte number	J:290567
	increased monocyte cell number	J:290567
	increased susceptibility to experimental autoimmune encephalomyelitis	J:290567
	thrombocytopenia	J:290567

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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