Slamf6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slamf6
SLAM family member 6
MGI:1353620

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slamf6^tm1Dhow/Slamf6^tm1Dhow involves: 129/Sv * C57BL/6	abnormal neutrophil physiology	J:98995
	abnormal T-helper 2 physiology	J:98995
	decreased interleukin-4 secretion	J:98995
	decreased susceptibility to parasitic infection	J:98995
	impaired granulocyte bactericidal activity	J:98995
	increased circulating interleukin-12b level	J:98995
	increased circulating interleukin-16 level	J:98995
	increased circulating tumor necrosis factor level	J:98995
	increased susceptibility to bacterial infection	J:98995
	increased susceptibility to bacterial infection induced morbidity/mortality	J:98995
Slamf6^tm1Lex/Slamf6^tm1Lex B6.129S5-Slamf6^tm1Lex	normal immune system phenotype	J:187429
Slamf6^tm1Lex/Slamf6^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	no abnormal phenotype detected	J:103485

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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