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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pttg1
pituitary tumor-transforming gene 1
MGI:1353578
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdc20Gt(XE368)Byg/Cdc20Gt(XE368)Byg
Pttg1tm1Pzg/Pttg1tm1Pzg
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal chromosome morphology J:121535
embryonic lethality before implantation, complete penetrance J:121535
Cdc20tm1.1Mama/Cdc20tm1.1Mama
Pttg1tm1.1Kna/Pttg1tm1.1Kna
involves: 129 * C57BL/6 * CD-1 * SJL 		abnormal mitosis J:167609
Espl1tm1.1Tno/Espl1+
Pttg1tm1.1Tno/Pttg1tm1.1Tno
involves: 129S4/SvJae * C57BL/6J 		decreased cell proliferation J:107917
Espl1tm1.2Kna/Espl1+
Pttg1tm1.2Kna/Pttg1tm1.2Kna
involves: 129P2/OlaHsd * C57BL/6 		abnormal cell death J:107916
abnormal cell nucleus morphology J:107916
abnormal mitosis J:107916
abnormal mitotic spindle morphology J:107916
abnormal neural tube morphology J:107916
abnormal somite development J:107916
decreased embryo size J:107916
embryonic lethality during organogenesis, complete penetrance J:107916
Espl1tm1.2Tno/Espl1+
Pttg1tm1.1Tno/Pttg1tm1.1Tno
involves: 129S4/SvJae * C57BL/6J 		embryonic growth retardation J:107917
embryonic lethality, complete penetrance J:107917
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory