Fscn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fscn1
fascin actin-bundling protein 1
MGI:1352745

26 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fscn1^{Gt(OST124903)Lex}/Fscn1⁺ Tg(Dct-lacZ)A12Jkn/0 involves: C57BL/6 * CBA	abnormal melanoblast morphology	J:197025
Fscn1^{Gt(OST124903)Lex}/Fscn1^{Gt(OST124903)Lex} B6.129S5-Fscn1^{Gt(OST124903)Lex}	abnormal anterior commissure pars posterior morphology	J:205179
	abnormal axon morphology	J:205179
	abnormal breathing pattern	J:205179
	abnormal cell cycle	J:197025
	abnormal dendritic cell chemotaxis	J:169408
	abnormal dendritic cell physiology	J:169408
	abnormal fibroblast physiology	J:205179
	abnormal Langerhans cell physiology	J:169408
	abnormal melanoblast morphology	J:197025
	abnormal neurite morphology	J:205179
	absent gastric milk in neonates	J:205179
	belly spot	J:197025
	decreased body size	J:205179
	decreased digit pigmentation	J:197025
	decreased melanocyte number	J:197025
	decreased tail pigmentation	J:197025
	enlarged lateral ventricles	J:205179
	neonatal lethality, incomplete penetrance	J:205179
	nervous	J:205179
Fscn1^{Gt(OST124903)Lex}/Fscn1^{Gt(OST124903)Lex} involves: 129S5/SvEvBrd * C57BL/6	normal mortality/aging	J:205179
Fscn1^{Gt(OST124903)Lex}/Fscn1^{Gt(OST124903)Lex} Tg(Dct-lacZ)A12Jkn/0 involves: C57BL/6 * CBA	abnormal melanoblast migration	J:197025
	abnormal melanoblast morphology	J:197025
	belly spot	J:197025
Fscn1^{tm1.1(KOMP)Vlcg}/Fscn1⁺ C57BL/6N-Fscn1^{tm1.1(KOMP)Vlcg}/Ucd	abnormal behavior	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
Fscn1^{tm1.1(KOMP)Vlcg}/Fscn1^{tm1.1(KOMP)Vlcg} C57BL/6N-Fscn1^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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