Cadps Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cadps
Ca2+-dependent secretion activator
MGI:1350922

17 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cadps^tm1.1Tfr/Cadps^tm1.2Tfr Emx1^tm1(cre)Ito/Emx1⁺ B6.Cg-Emx1^tm1(cre)Ito Cadps^tm1.1Tfr Cadps^tm1.2Tfr	abnormal dentate gyrus morphology	J:204664
	abnormal Golgi trans cisterna morphology	J:204664
	abnormal hippocampus pyramidal cell morphology	J:204664
	abnormal synaptic bouton morphology	J:204664
	normal nervous system phenotype	J:204664
Cadps^tm1.1Tfr/Cadps^tm1.2Tfr Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ B6.Cg-Ptf1a^{tm1.1(cre)Cvw} Cadps^tm1.1Tfr Cadps^tm1.2Tfr	abnormal cerebellar molecular layer	J:204664
	abnormal paired-pulse inhibition	J:204664
	abnormal synaptic bouton morphology	J:204664
	abnormal synaptic vesicle number	J:204664
	decreased excitatory postsynaptic current amplitude	J:204664
	normal nervous system phenotype	J:204664
Cadps^tm1Bros/Cadps⁺ Not Specified	abnormal adrenal gland secretion	J:99762
Cadps^tm1Bros/Cadps^tm1Bros Not Specified	abnormal adrenal gland physiology	J:99762
	abnormal adrenal gland secretion	J:99762
	abnormal neuron morphology	J:131212
	abnormal neuron physiology	J:131212
	decreased excitatory postsynaptic current amplitude	J:131212
	decreased miniature excitatory postsynaptic current amplitude	J:131212
	decreased miniature excitatory postsynaptic current frequency	J:131212
	neonatal lethality, complete penetrance	J:99762
	normal nervous system phenotype	J:99762
	respiratory failure	J:99762

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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