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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
MGI:1349475
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ppp2r5aGt(IST13127C10)Tigm/Ppp2r5aGt(IST13127C10)Tigm
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5cGt(XP0444)Wtsi
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N 		neonatal lethality, incomplete penetrance J:348684
ventricular septal defect J:348684
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5c+
Ppp2r5eGt(YHD256)Byg/Ppp2r5e+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J 		normal cardiovascular system phenotype J:348684
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5c+
Ppp2r5eGt(YHD256)Byg/Ppp2r5eGt(YHD256)Byg
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J 		normal cardiovascular system phenotype J:348684
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5cGt(XP0444)Wtsi
Ppp2r5dGt(RRT114)Byg/Ppp2r5dGt(RRT114)Byg
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J 		abnormal cell cycle J:348684
abnormal heart development J:348684
abnormal limb development J:348684
normal behavior/neurological phenotype J:348684
decreased fetal size J:348684
decreased fibroblast proliferation J:348684
embryonic growth arrest J:348684
embryonic lethality, complete penetrance J:348684
increased fetal cardiomyocyte apoptosis J:348684
normal nervous system phenotype J:348684
pericardial edema J:348684
persistent truncus arteriosus J:348684
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5cGt(XP0444)Wtsi
Ppp2r5eGt(YHD256)Byg/Ppp2r5eGt(YHD256)Byg
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J 		abnormal heart development J:348684
abnormal heart right ventricle morphology J:348684
postnatal lethality, complete penetrance J:348684
ventricular septal defect J:348684
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory