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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sh2d1b1
SH2 domain containing 1B1
MGI:1349420
5 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Sh2d1b1/Sh2d1b2tm1.1Cpt/Sh2d1b1/Sh2d1b2tm1.1Cpt
involves: BALB/cJ
decreased interferon-gamma secretion J:166054
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b1tm1.1Cpt/Sh2d1b1tm1.1Cpt
involves: BALB/cJ * C57BL/6
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b1tm1Vei/Sh2d1b1tm1Vei
involves: 129S1/Sv * 129X1/SvJ
increased interferon-gamma secretion J:110195
increased natural killer cell mediated cytotoxicity J:110195
Sh2d1b1tm3Vei/Sh2d1b1tm3Vei
involves: C57BL/6
abnormal NK cell physiology J:187430
Tg(CD2-Sh2d1b1)#Vei/0
B6.Cg-Tg(CD2-Sh2d1b1)#Vei
decreased interferon-gamma secretion J:110195
impaired natural killer cell mediated cytotoxicity J:110195

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory