Aifm1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
MGI:1349419

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aifm1^Hq/Aifm1^Hq Apaf1^{Gt(IRESBetageo)XIX18Pgr}/Apaf1^{Gt(IRESBetageo)XIX18Pgr} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	decreased neuron apoptosis	J:98103
Apaf1^{Gt(IRESBetageo)XIX18Pgr}/Apaf1^{Gt(IRESBetageo)XIX18Pgr} Aifm1^tm2Pngr/Y Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal mitochondrial physiology	J:112874
	decreased neuron apoptosis	J:112874
	increased neuron apoptosis	J:112874
	thickened cerebral cortex	J:112874

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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