Aifm1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
MGI:1349419

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aifm1^Hq/Aifm1⁺ B6CBACa A^w-J/A-Aifm1^Hq/J	normal behavior/neurological phenotype	J:79052
	normal nervous system phenotype	J:79052
	sparse hair	J:79052
Aifm1^Hq/Aifm1^Hq Apaf1^{Gt(IRESBetageo)XIX18Pgr}/Apaf1^{Gt(IRESBetageo)XIX18Pgr} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	decreased neuron apoptosis	J:98103
Apaf1^{Gt(IRESBetageo)XIX18Pgr}/Apaf1^{Gt(IRESBetageo)XIX18Pgr} Aifm1^tm2Pngr/Y Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal mitochondrial physiology	J:112874
	decreased neuron apoptosis	J:112874
	increased neuron apoptosis	J:112874
	thickened cerebral cortex	J:112874
Gt(ROSA)26Sor^{tm8(Aifm1)Jhai}/Gt(ROSA)26Sor⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA	normal mortality/aging	J:194078
Gt(ROSA)26Sor^{tm9(Aifm1)Jhai}/Gt(ROSA)26Sor⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S6/SvEvTac C57BL/6 * C57BL/6NCr * CBA	normal mortality/aging	J:194078

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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