Ror1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ror1
receptor tyrosine kinase-like orphan receptor 1
MGI:1347520

26 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ror1^{em1(IMPC)Ccpcz}/Ror1⁺ C57BL/6NCrl-Ror1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	hydrometra	J:211773
	increased prepulse inhibition	J:211773
	small kidney	J:211773
Ror1^{em1(IMPC)Ccpcz}/Ror1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Ror1^{em1(IMPC)Ccpcz}/Ccpcz	preweaning lethality, complete penetrance	J:211773
Ror1^tm1.2Meg/Ror1^tm1.2Meg involves: 129S4/SvJae * C57BL/6 * FVB/N	exencephaly	J:182150
Ror1^tm1Ymi/Ror1^tm1Ymi involves: 129P2/OlaHsd	abnormal axon fasciculation	J:232175
	abnormal cochlea morphology	J:232175
	abnormal cochlear hair cell morphology	J:232175
	abnormal ribbon synapse morphology	J:232175
	abnormal sensory neuron innervation pattern	J:232175
	abnormal synapse morphology	J:232175
	deafness	J:232175
	decreased cochlea coiling	J:232175
	decreased distortion product otoacoustic emission amplitude	J:232175
	increased or absent threshold for auditory brainstem response	J:232175
Ror1^tm1Ymi/Ror1^tm1Ymi involves: 129P2/OlaHsd * C57BL/6	abnormal blood homeostasis	J:72948
	abnormal pulmonary alveolus morphology	J:72948
	abnormal respiratory system physiology	J:72948
	cyanosis	J:72948
	neonatal lethality, complete penetrance	J:72948
	respiratory distress	J:72948

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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