Best1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Best1
bestrophin 1
MGI:1346332

18 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Best1^tm1.1Amar/Best1⁺ involves: 129X1/SvJ * BALB/c	abnormal eye electrophysiology	J:157645
	abnormal eye physiology	J:157645
	abnormal retina pigment epithelium morphology	J:157645
	retina detachment	J:157645
Best1^tm1.1Amar/Best1^tm1.1Amar involves: 129X1/SvJ * BALB/c	abnormal eye electrophysiology	J:157645
	abnormal eye physiology	J:157645
	abnormal retina pigment epithelium morphology	J:157645
	retina detachment	J:157645
Best1^tm1Lmar/Best1^tm1Lmar involves: 129X1/SvJ * C57BL/6	abnormal eye electrophysiology	J:136113
Best1^tm1Lmar/Best1^tm1Lmar involves: 129X1/SvJ * C57BL/6	abnormal eye physiology	J:136113
Best1^tm1Web/Best1^tm1Web B6.129S1-Best1^tm1Web	abnormal acrosome morphology	J:221655
	abnormal sperm flagellum morphology	J:221655
	decreased litter size	J:221655
	reduced male fertility	J:221655
	normal vision/eye phenotype	J:221655
Best1^tm1Web/Best1^tm1Web involves: CD-1	abnormal acrosome morphology	J:221655
	abnormal sperm physiology	J:221655
	absent acrosome	J:221655
	asthenozoospermia	J:221655
	coiled sperm flagellum	J:221655
	detached sperm flagellum	J:221655
	kinked sperm flagellum	J:221655
	necrospermia	J:221655
	reduced male fertility	J:221655
	normal vision/eye phenotype	J:221655
Best1^tm2.1Web/Best1^tm2.1Web B6.129S1(Cg)-Best1^tm2.1Web	normal reproductive system phenotype	J:280642
Best1^tm2.1Web/Best1^tm2.1Web B6.129S1(Cg)-Best1^tm2.1Web	normal vision/eye phenotype	J:280642
Best1^tm2.1Web/Best1^tm2.1Web involves: 129S1/Sv * CD-1	asthenozoospermia	J:280642
Best1^tm2.1Web/Best1^tm2.1Web involves: 129S1/Sv * CD-1	impaired fertilization	J:280642

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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