64 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mesp1tm2(cre)Ysa/Mesp1+ Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal cardiac epithelial to mesenchymal transition	J:143444
	abnormal cardiac outflow tract development	J:143444
	abnormal heart development	J:143444
	abnormal heart morphology	J:143444
	atrioventricular septal defect	J:143444
	bicuspid aortic valve	J:143444
	double outlet right ventricle	J:143444
	persistent truncus arteriosus	J:143444
	ventricular septal defect	J:143444
Pax3tm1(cre)Joe/Pax3+ Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 Not Specified	normal cardiovascular system phenotype	J:143444
	short mandible	J:143444
	short snout	J:143444
Spry2tm1.1Mrt/Spry2tm1.1Mrt involves: 129/Sv * 129P2/OlaHsd * Black Swiss * C57BL/6 * FVB/N	abnormal auditory brainstem response waveform shape	J:98303
	abnormal Claudius cell morphology	J:98303
	abnormal digestive system physiology	J:98303
	abnormal organ of Corti morphology	J:98303
	abnormal organ of Corti supporting cell morphology	J:98303
	abnormal pillar cell morphology	J:98303
	decreased body size	J:98303
	increased cochlear outer hair cell number	J:98303
	increased Deiters cell number	J:98303
	increased or absent threshold for auditory brainstem response	J:98303
	postnatal lethality, incomplete penetrance	J:98303
Spry2tm1.1Mrt/Spry2tm1.1Mrt involves: 129P2/OlaHsd	abnormal chondrocyte morphology	J:315670
	abnormal craniofacial bone morphology	J:315670
	abnormal diastema morphology	J:119280
	abnormal mandible morphology	J:315670
	abnormal mandibular condyloid process morphology	J:315670
	abnormal mandibular coronoid process morphology	J:315670
	abnormal maxillary shelf morphology	J:315670
	abnormal molar cusp morphology	J:119280
	abnormal neurocranium morphology	J:315670
	abnormal primary cilium morphology	J:315670
	abnormal temporal bone morphology	J:315670
	abnormal tooth development	J:119280
	abnormal tooth morphology	J:315670
	abnormal vertebral arch morphology	J:315670
	abnormal vertebral spinous process morphology	J:315670
	abnormal vertebral transverse process morphology	J:315670
	cleft palate	J:315670
	complete cleft palate	J:315670
	decreased bone mineral density	J:315670
	decreased length of long bones	J:315670
	decreased trabecular bone mass	J:315670
	enlarged frontal bone	J:315670
	enlarged interparietal bone	J:315670
	increased cranium height	J:315670
	increased long bone epiphyseal plate size	J:315670
	malocclusion	J:315670
	short nasal bone	J:315670
	short snout	J:315670
	small neurocranium	J:315670
	small supraoccipital bone	J:315670
	small vertebral body	J:315670
	spinal stenosis	J:315670
	supernumerary teeth	J:119280, J:315670
	wide intermaxillary suture	J:315670
Spry2tm1Ayos/Spry2tm1Ayos B6.Cg-Spry2tm1Ayos	abnormal digestive system physiology	J:99827
	abnormal enteric ganglia morphology	J:99827
	abnormal enteric nervous system morphology	J:99827
	abnormal enteric neuron morphology	J:99827
	abnormal intestine morphology	J:99827
	decreased body size	J:99827
	dilated esophagus	J:99827
	intestinal obstruction	J:99827
	premature death	J:99827
Spry2tm1Mrt/Spry2tm1Mrt involves: 129P2/OlaHsd	increased lung tumor incidence	J:119477