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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Spop
speckle-type BTB/POZ protein
MGI:1343085
31 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
SpopGt(BGB118)Byg/Spop+
involves: 129P2/OlaHsd * C57BL/6
abnormal pancreatic beta cell physiology J:165268
abnormal pancreatic islet cell apoptosis J:165268
normal endocrine/exocrine gland phenotype J:165268
normal homeostasis/metabolism phenotype J:165268
SpopGt(BGB118)Byg/SpopGt(BGB118)Byg
involves: 129P2/OlaHsd * C57BL/6
increased pancreatic beta cell mass J:165268
perinatal lethality, complete penetrance J:165268
Spoptm1a(KOMP)Mbp/Spoptm1a(KOMP)Mbp
involves: C57BL/6N
neonatal lethality, complete penetrance J:239074
Spoptm1b(KOMP)Wtsi/Spop+
C57BL/6N-Spoptm1b(KOMP)Wtsi/Tcp
decreased food intake J:211773
decreased grip strength J:211773
decreased prepulse inhibition J:211773
decreased respiratory quotient J:211773
enlarged lymph nodes J:211773
increased circulating aspartate transaminase level J:211773
small adrenal glands J:211773
small thymus J:211773
Spoptm1b(KOMP)Wtsi/Spoptm1b(KOMP)Wtsi
C57BL/6N-Spoptm1b(KOMP)Wtsi/Tcp
preweaning lethality, complete penetrance J:211773
Spoptm1c(KOMP)Mbp/Spoptm1c(KOMP)Mbp
Tg(Prrx1-cre)1Cjt/0
involves: C57BL/6J * C57BL/6N * SJL/J
abnormal bone ossification J:239074
abnormal femur morphology J:239074
abnormal trabecular bone morphology J:239074
brachydactyly J:239074
brachyphalangia J:239074
decreased bone mass J:239074
decreased bone mineral density J:239074
decreased bone trabecula number J:239074
decreased bone volume J:239074
decreased length of long bones J:239074
decreased trabecular bone connectivity density J:239074
decreased trabecular bone mass J:239074
decreased trabecular bone thickness J:239074
short metacarpal bones J:239074
short metatarsal bones J:239074
Spoptm1d(KOMP)Mbp/Spoptm1d(KOMP)Mbp
involves: C57BL/6N * FVB/N
neonatal lethality, complete penetrance J:239074

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory