Six6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Six6
sine oculis-related homeobox 6
MGI:1341840

26 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Six6^tm1Rsd/Six6^tm1Rsd either: 129 or (involves: 129S1/Sv * 129X1/SvJ)	abnormal retina ganglion layer morphology	J:104339
	abnormal retina morphology	J:104339
	absent optic nerve	J:104339
	pituitary gland hypoplasia	J:104339
	retina hypoplasia	J:104339
Six6^tm1Rsd/Six6^tm1Rsd involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal axon morphology	J:168233
	abnormal neuroendocrine cell morphology	J:168233
	abnormal ovary morphology	J:168233
	abnormal protein level	J:168233
	anovulation	J:168233
	decreased circulating follicle stimulating hormone level	J:168233
	decreased copulatory plug deposition	J:168233
	decreased corpora lutea number	J:168233
	decreased neuron number	J:168233
	decreased ovary weight	J:168233
	decreased seminal vesicle weight	J:168233
	normal homeostasis/metabolism phenotype	J:168233
	ovarian follicular cyst	J:168233
	prolonged estrous cycle	J:168233
	prolonged estrus	J:168233
	reduced female fertility	J:168233
	reduced male fertility	J:168233
	normal reproductive system phenotype	J:168233
	short metestrus	J:168233
	short proestrus	J:168233
	small ovary	J:168233

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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