Tlr6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tlr6
toll-like receptor 6
MGI:1341296

9 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tlr6^int/Tlr6^int C57BL/6-Tlr6^int	abnormal adaptive immunity	J:110094
	abnormal cell-mediated immunity	J:110094
	abnormal innate immunity	J:110094
	abnormal macrophage physiology	J:110094
Tlr6^m2Btlr/Tlr6^m2Btlr C57BL/6J-Tlr6^m2Btlr	abnormal macrophage physiology	J:144166
Tlr6^m2Btlr/Tlr6^m2Btlr C57BL/6J-Tlr6^m2Btlr	decreased tumor necrosis factor secretion	J:144166
Tlr6^m3Btlr/Tlr6^m3Btlr C57BL/6J-Tlr6^m3Btlr	abnormal macrophage physiology	J:144167
Tlr6^m3Btlr/Tlr6^m3Btlr C57BL/6J-Tlr6^m3Btlr	decreased tumor necrosis factor secretion	J:144167
Tlr6^m4Btlr/Tlr6^m4Btlr C57BL/6J-Tlr6^m4Btlr	abnormal macrophage physiology	J:144168
	decreased tumor necrosis factor secretion	J:144168
	male infertility	J:144168
Tlr6^tm1Aki/Tlr6^tm1Aki involves: 129P2/OlaHsd * C57BL/6	abnormal cytokine secretion	J:70578
	abnormal macrophage physiology	J:70578
	decreased interleukin-6 secretion	J:70578
	decreased interleukin-12 secretion	J:70578
	decreased tumor necrosis factor secretion	J:70578

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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