Gldc Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gldc
glycine decarboxylase
MGI:1341155

29 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gldc^b2b2679Clo/Gldc^b2b2679Clo C57BL/6J-Gldc^b2b2679Clo	absent mandible	J:175213
	anophthalmia	J:175213
	cleft palate	J:175213
	cleft upper lip	J:175213
	double outlet right ventricle	J:175213
	hydronephrosis	J:175213
	kidney cyst	J:175213
	omphalocele	J:175213
	short snout	J:175213
	ventricular septal defect	J:175213
Gldc^{Gt(EUCG0001d02)Hmgu}/Gldc^{Gt(EUCG0001d02)Hmgu} B6.129P2-Gldc^{Gt(EUCG0001d02)Hmgu}	abnormal embryonic neuroepithelium morphology	J:221782
	abnormal folic acid level	J:221782
	abnormal neural tube morphology	J:221782
	decreased survivor rate	J:221782
	domed cranium	J:221782
	embryonic growth retardation	J:221782
	enlarged brain ventricles	J:221782
	enlarged cranium	J:221782
	exencephaly	J:221782
	hydrocephaly	J:221782
	hyperglycinuria	J:221782
	incomplete rostral neuropore closure	J:221782
	increased circulating glycine level	J:221782
	intracranial hemorrhage	J:221782
	open neural tube	J:221782
	postnatal lethality, incomplete penetrance	J:221782
	premature death	J:221782
Gldc^{tm1a(EUCOMM)Wtsi}/Gldc⁺ C57BL/6N-Gldc^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal vertebral arch morphology	J:211773
Gldc^{tm1a(EUCOMM)Wtsi}/Gldc^{tm1a(EUCOMM)Wtsi} C57BL/6N-Gldc^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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