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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Padi4
peptidyl arginine deiminase, type IV
MGI:1338898
28 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Padi4em1(IMPC)Mbp/Padi4em1(IMPC)Mbp
C57BL/6N-Padi4em1(IMPC)Mbp/MbpMmucd
abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal lymph node morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal uterus morphology J:211773
decreased circulating cholesterol level J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged liver J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased circulating bilirubin level J:211773
increased circulating triglyceride level J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
small heart J:211773
small kidney J:211773
small liver J:211773
Padi4tm1.1Kmow/Padi4tm1.1Kmow
involves: BALB/cJ * C57BL/6
abnormal neutrophil physiology J:174934
decreased susceptibility to Orthomyxoviridae infection J:174934
decreased susceptibility to weight loss J:174934
Padi4tm1.1Kmow/Padi4tm1.1Kmow
Tg(CMV-cre)1Cgn/0
involves: BALB/cJ * C57BL/6
normal immune system phenotype J:190651
Padi4tm1.1Ywan/Padi4+
involves: 129S4/SvJae
lethality, incomplete penetrance J:165718
Padi4tm1.1Ywan/Padi4tm1.1Ywan
involves: 129S4/SvJae
abnormal neutrophil physiology J:165718
impaired neutrophil phagocytosis J:165718
increased susceptibility to bacterial infection J:165718
lethality, incomplete penetrance J:165718
Padi4tm1.2Kmow/Padi4tm1.2Kmow
involves: C57BL/6 * SJL
no abnormal phenotype detected J:174934
Padi4tm1Ywan/Padi4tm1Ywan
involves: 129S4/SvJae
no abnormal phenotype detected J:165718

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory