Spint2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spint2
serine protease inhibitor, Kunitz type 2
MGI:1338031

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F2rl1^tm1Cgh/F2rl1^tm1Cgh Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * 129S4/SvJae	embryonic lethality, complete penetrance	J:188121
F2rl1^tm1Cgh/F2rl1^tm1Cgh Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14⁺ involves: 129P2/OlaHsd * 129S4/SvJae	exencephaly	J:188121
Prss8^em1Bug/Prss8^em1Bug Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/NJ * NIH Black Swiss	abnormal digestive system morphology	J:261068
	abnormal enterocyte proliferation	J:261068
	abnormal intestinal epithelium morphology	J:261068
	abnormal intestinal goblet cell morphology	J:261068
	abnormal intestine morphology	J:261068
	abnormal large intestine crypts of Lieberkuhn morphology	J:261068
	abnormal large intestine morphology	J:261068
	abnormal small intestine morphology	J:261068
	decreased birth weight	J:261068
	decreased colon goblet cell number	J:261068
	decreased intestine length	J:261068
	intestinal hemorrhage	J:261068
	postnatal growth retardation	J:261068
	postnatal lethality, complete penetrance	J:261068
	small intestinal villus atrophy	J:261068
Prss8^fr/Prss8⁺ Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * DBA	embryonic lethality, complete penetrance	J:188121
Prss8^fr/Prss8^fr Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * DBA	normal embryo phenotype	J:188121
	exencephaly	J:188121
	prenatal lethality, incomplete penetrance	J:188121
Prss8^fr/Prss8^fr Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14⁺ involves: 129P2/OlaHsd * DBA	normal embryo phenotype	J:188121
	normal mortality/aging	J:188121
Scnn1a^tm1.2Hum/Scnn1a^tm1.2Hum Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129/Sv * 129P2/OlaHsd	embryonic lethality, complete penetrance	J:188121
Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14⁺ involves: 129P2/OlaHsd	abnormal placenta labyrinth morphology	J:188121
	abnormal placenta morphology	J:188121
	curly tail	J:188121
	embryonic lethality between implantation and placentation, incomplete penetrance	J:188121
	embryonic lethality during organogenesis, incomplete penetrance	J:188121
	exencephaly	J:188121
	lethality throughout fetal growth and development, complete penetrance	J:188121
	spina bifida	J:188121
Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14^tm1Bug involves: 129P2/OlaHsd	abnormal neural tube morphology	J:188121
	curly tail	J:188121
	normal embryo phenotype	J:188121
	exencephaly	J:188121
	normal mortality/aging	J:188121
	spina bifida	J:188121

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