Irs4 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irs4
insulin receptor substrate 4
MGI:1338009

9 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irs4^tm1Lhd/Y involves: 129S4/SvJae * BALB/c	abnormal fertility/fecundity	J:59964
	decreased litter size	J:59964
	impaired glucose tolerance	J:59964
Irs4^tm1Lhd/Y involves: 129S4/SvJae * C57BL/6	abnormal fertility/fecundity	J:59964
	decreased body weight	J:59964
	decreased circulating glucose level	J:59964
	decreased litter size	J:59964
	impaired glucose tolerance	J:59964
	postnatal growth retardation	J:59964
Irs4^tm1Lhd/Irs4^tm1Lhd involves: 129S4/SvJae * BALB/c	abnormal fertility/fecundity	J:59964
Irs4^tm1Lhd/Irs4^tm1Lhd involves: 129S4/SvJae * BALB/c	decreased litter size	J:59964
Irs4^tm1Lhd/Irs4^tm1Lhd involves: 129S4/SvJae * C57BL/6	abnormal fertility/fecundity	J:59964
	abnormal glucose tolerance	J:59964
	abnormal maternal nurturing	J:59964
	decreased litter size	J:59964
	normal growth/size/body region phenotype	J:59964
	normal homeostasis/metabolism phenotype	J:59964

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/15/2026 MGI 6.29