Nr1i2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr1i2
nuclear receptor subfamily 1, group I, member 2
MGI:1337040

9 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nr1i2^tm1Rev/Nr1i2^tm1Rev involves: 129S4/SvJae * C57BL/6J	decreased physiological sensitivity to xenobiotic	J:63639
Nr1i2^tm1Sakl/Nr1i2^tm1Sakl involves: 129S1/Sv * 129X1/SvJ	decreased hepatocyte proliferation	J:157882
Nr1i2^tm1Sakl/Nr1i2^tm1Sakl involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal physiological response to xenobiotic	J:103505
	decreased liver enzyme/coenzyme level	J:103505
	decreased physiological sensitivity to xenobiotic	J:103235
	impaired behavioral response to xenobiotic	J:103505
	increased liver enzyme/coenzyme level	J:103505
Nr1i2^tm3Arte/Nr1i2^tm3Arte involves: C57BL/6	decreased physiological sensitivity to xenobiotic	J:140975
	normal liver/biliary system phenotype	J:140975
	normal mortality/aging	J:140975
	normal reproductive system phenotype	J:140975

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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