Gjd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gjd2
gap junction protein, delta 2
MGI:1334209

21 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gjd2^tm1Kwi/Gjd2^tm1Kwi involves: 129P2/OlaHsd	abnormal nervous system electrophysiology	J:99856
	abnormal retina ganglion layer morphology	J:98181
	decreased insulin secretion	J:117402
	normal digestive/alimentary phenotype	J:117402
Gjd2^tm1Kwi/Gjd2^tm1Kwi involves: 129P2/OlaHsd * C57BL/6	abnormal cued conditioning behavior	J:145292
	abnormal insulin secretion	J:122093
	abnormal nerve fiber response	J:145292
	abnormal pancreatic beta cell physiology	J:122093
	abnormal single cell response	J:145292
	normal behavior/neurological phenotype	J:145292
	normal digestive/alimentary phenotype	J:122093
Gjd2^tm1Mony/Gjd2^tm1Mony Not Specified	abnormal action potential	J:71116
	abnormal brain wave pattern	J:71116
	abnormal CNS synaptic transmission	J:71116
	abnormal excitatory postsynaptic potential	J:71116
	abnormal inhibitory postsynaptic potential	J:71116
	normal nervous system phenotype	J:71116
Gjd2^tm1Paul/Gjd2^tm1Paul involves: 129S4/SvJae * C57BL/6	abnormal CNS synaptic transmission	J:71117
Gjd2^tm1Paul/Gjd2^tm1Paul involves: 129S4/SvJae * C57BL/6	normal nervous system phenotype	J:71117
Gjd2^tm2Kwi/Gjd2^tm4Kwi Tg(Pvalb-cre)1Mony/? involves: 129P2/OlaHsd	normal behavior/neurological phenotype	J:145292
Gjd2^tm4Kwi/Gjd2^tm4Kwi involves: 129P2/OlaHsd * C57BL/6	normal endocrine/exocrine gland phenotype	J:174834
Gjd2^tm4Kwi/Gjd2^tm4Kwi involves: 129P2/OlaHsd * C57BL/6	normal vision/eye phenotype	J:174834
Gjd2^tm4Kwi/Gjd2^tm4Kwi Tg(Ins2-cre)23Herr/? involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal glucose tolerance	J:174834
	abnormal pancreatic beta cell physiology	J:174834
	normal homeostasis/metabolism phenotype	J:174834
	increased insulin secretion	J:174834

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23