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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gab2
growth factor receptor bound protein 2-associated protein 2
MGI:1333854
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Gab1tm1Nmoc/Gab1tm1Nmoc
Gab2tm1Thir/Gab2tm1Thir
Tg(Myh6-cre)2182Mds/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
abnormal cardiac muscle relaxation J:124033
abnormal endocardium morphology J:124033
abnormal heart left ventricle morphology J:124033
abnormal heart morphology J:124033
congestive heart failure J:124033
decreased cardiac muscle contractility J:124033
dilated heart J:124033
increased heart weight J:124033
increased left ventricle diastolic pressure J:124033
premature death J:124033
thin interventricular septum J:124033
Gab2tm2.1Thir/Gab2tm2.1Thir
involves: 129T/SvJcl * C57BL/6Jcl
normal immune system phenotype J:178045
Gab2tm3.1Thir/Gab2tm3.1Thir
involves: 129T/SvJcl * C57BL/6Jcl
decreased mast cell degranulation J:178045
decreased mast cell number J:178045
decreased susceptibility to type I hypersensitivity reaction J:178045
normal immune system phenotype J:178045

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory