Mbd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mbd2
methyl-CpG binding domain protein 2
MGI:1333813

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mbd2^em1(IMPC)Bay/Mbd2^em1(IMPC)Bay C57BL/6N-Mbd2^em1(IMPC)Bay/Bay	abnormal retina morphology	J:211773
	abnormal retina outer nuclear layer morphology	J:211773
	increased cornea thickness	J:211773
Mbd2^tm1Bh/Mbd2^tm1Bh involves: 129P2/OlaHsd * C57BL/6	abnormal maternal nurturing	J:68356
	abnormal pup retrieval	J:68356
	decreased litter size	J:68356
Mbd2^tm1Bh/Mbd2^tm1Bh NOD.129P2(B6)-Mbd2^tm1Bh	abnormal CD4-positive, alpha-beta T cell physiology	J:323838
	abnormal CD8-positive, alpha-beta cytotoxic T cell morphology	J:323838
	abnormal effector T cell morphology	J:323838
	abnormal homeostasis	J:323838
	abnormal pancreatic islet morphology	J:323838
	enlarged lymph nodes	J:323838
	enlarged spleen	J:323838
	hyperglycemia	J:323838
	increased T cell proliferation	J:323838
	increased T-helper 1 cell number	J:323838
	increased T-helper 2 cell number	J:323838
	insulitis	J:323838
	salivary gland inflammation	J:323838

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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