Cd2ap Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd2ap
CD2-associated protein
MGI:1330281

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd2ap^em1(IMPC)Bay/Cd2ap^em1(IMPC)Bay C57BL/6N-Cd2ap^em1(IMPC)Bay/BayMmucd	decreased grip strength	J:211773
Cd2ap^em1Irgu/Cd2ap^em1Irgu C57BL/6-Cd2ap^em1Irgu	albuminuria	J:294238
	decreased circulating serum albumin level	J:294238
	glomerulosclerosis	J:294238
	increased blood urea nitrogen level	J:294238
	increased circulating creatinine level	J:294238
	increased urine protein level	J:294238
	kidney failure	J:294238
	kidney inflammation	J:294238
	postnatal growth retardation	J:294238
	premature death	J:294238
	renal tubule atrophy	J:294238
Cd2ap^tm1Shaw/Cd2ap⁺ Not Specified	abnormal kidney physiology	J:84748
	abnormal podocyte morphology	J:84748
	abnormal renal glomerulus morphology	J:84748
	expanded mesangial matrix	J:84748
	increased mesangial cell number	J:84748
	increased susceptibility to injury	J:84748
Cd2ap^tm1Shaw/Cd2ap^tm1Shaw involves: 129X1/SvJ	abnormal podocyte morphology	J:57971
	ascites	J:57971
	decreased circulating serum albumin level	J:57971
	decreased T cell proliferation	J:57971
	enlarged heart	J:57971
	glomerulosclerosis	J:57971
	increased blood urea nitrogen level	J:57971
	increased circulating creatinine level	J:57971
	increased mesangial cell number	J:57971
	increased urine protein level	J:57971
	postnatal growth retardation	J:57971
	premature death	J:57971
	renal glomerulus hypertrophy	J:57971
	spleen atrophy	J:57971
	thymus atrophy	J:57971

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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