Emg1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Emg1
EMG1 N1-specific pseudouridine methyltransferase
MGI:1315195

23 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emg1^{tm1.1(KOMP)Wtsi}/Emg1⁺ C57BL/6N-Emg1^{tm1.1(KOMP)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	decreased circulating aspartate transaminase level	J:211773
	decreased total retina thickness	J:211773
Emg1^{tm1.1(KOMP)Wtsi}/Emg1^{tm1.1(KOMP)Wtsi} C57BL/6N-Emg1^{tm1.1(KOMP)Wtsi}/Bay	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Emg1^tm1.1Btr/Emg1^tm1.1Btr involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	abnormal placenta labyrinth morphology	J:230556
	abnormal telencephalon development	J:230556
	decreased cell proliferation	J:230556
	decreased embryo size	J:230556
	decreased erythrocyte cell number	J:230556
	embryonic growth retardation	J:230556
	embryonic lethality during organogenesis, complete penetrance	J:230556
	exencephaly	J:230556
	incomplete rostral neuropore closure	J:230556
	increased apoptosis	J:230556
	open neural tube	J:230556
	wavy neural tube	J:230556
Emg1^tm1Hdin/Emg1^tm1Hdin involves: 129S1/Sv * 129X1/SvJ * CD-1 * ICR	abnormal nucleolus morphology	J:165972
	abnormal preimplantation embryo development	J:165972
	absent blastocoele	J:165972
	absent inner cell mass	J:165972
	embryonic growth arrest	J:165972
	embryonic lethality before implantation, complete penetrance	J:165972

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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