Rasgrp1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rasgrp1
RAS guanyl releasing protein 1
MGI:1314635

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^m1Anu/Cd79a^m1Anu Rasgrp1^m1Anu/Rasgrp1^m1Anu involves: C57BL/6JSfdAnu * CBA/J	normal immune system phenotype	J:207898
Mtor^chino/Mtor^chino Rasgrp1^m1Anu/Rasgrp1^m1Anu involves: C57BL/6JAnu * C57BL/6JSfdAnu * CBA/J	normal hematopoietic system phenotype	J:207898
	normal immune system phenotype	J:207898
Rasgrp1^tm1.1Wz/Rasgrp1^tm1.1Wz Tg(TcraH-Y,TcrbH-Y)71Vbo/? involves: C57BL/6J * DBA/2J	decreased single-positive T cell number	J:225109
	increased double-positive T cell number	J:225109
Rasgrp1^tm1.1Wz/Rasgrp1^tm1.1Wz Tg(TcraTcrb)425Cbn/? involves: C57BL/6 * BALB/c	abnormal CD4-positive T cell differentiation	J:225109
Rasgrp1^tm1Jstn/Rasgrp1^tm1Jstn Rasgrp3^tm1Jstn/Rasgrp3^tm1Jstn involves: 129P3/J * C57BL/6J	abnormal humoral immune response	J:108677
	decreased B cell number	J:108677
	decreased plasma cell number	J:108677

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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