Slfn2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slfn2
schlafen 2
MGI:1313258

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slfn2^m1Btlr/Slfn2^m1Btlr C57BL/6J-Slfn2^m1Btlr	abnormal leukocyte physiology	J:158985
	abnormal nitric oxide homeostasis	J:158985
	abnormal T cell activation	J:158985
	abnormal T cell proliferation	J:158985
	decreased CD4-positive, alpha-beta T cell number	J:158985
	decreased CD8-positive, alpha-beta T cell number	J:158985
	decreased monocyte cell number	J:158985
	decreased T cell proliferation	J:158985
	increased neutrophil cell number	J:158985
	increased susceptibility to bacterial infection	J:158985
	increased susceptibility to bacterial infection induced morbidity/mortality	J:158985
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:158985
	increased susceptibility to Riboviria infection	J:158985
	increased T cell apoptosis	J:158985
Slfn2^m2Btlr/Slfn2^m2Btlr C57BL/6J-Slfn2^m2Btlr	decreased IgG level	J:234262
	decreased response to antigen	J:234262
	impaired humoral immune response	J:234262

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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