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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dhcr7
7-dehydrocholesterol reductase
MGI:1298378
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dhcr7tm1Gst/Dhcr7tm1Gst
Tg(APOE-DHCR7)2Hoyu/0
involves: 129P2/OlaHsd * C57BL * C57BL/6J * FVB/N 		abnormal suckling reflex J:141730
decreased brain cholesterol level J:141730
decreased circulating cholesterol level J:141730
decreased liver cholesterol level J:141730
decreased lung cholesterol level J:141730
hypotonia J:141730
impaired lung alveolus development J:141730
postnatal lethality, complete penetrance J:141730
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory