Cabin1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cabin1
calcineurin binding protein 1
MGI:1298375

22 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cabin1^{em1(IMPC)Ccpcz}/Cabin1⁺ C57BL/6NCrl-Cabin1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased lung elastance	J:211773
	enlarged heart	J:211773
	enlarged thymus	J:211773
Cabin1^{em1(IMPC)Ccpcz}/Cabin1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Cabin1^{em1(IMPC)Ccpcz}/Ccpcz	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Cabin1^em1Dcfaj/Cabin1^em1Dcfaj C57BL/6J-Cabin1^em1Dcfaj	normal immune system phenotype	J:378928
Cabin1^em1Dcfaj/Cabin1^em1Dcfaj C57BL/6J-Cabin1^em1Dcfaj	normal mortality/aging	J:378928
Cabin1^em1Dcfaj/Cabin1^em2Dcfaj C57BL/6J-Cabin1^em1Dcfaj Cabin1^em2Dcfaj	normal immune system phenotype	J:378928
	increased susceptibility to Riboviria infection induced morbidity/mortality	J:378928
	normal mortality/aging	J:378928
Cabin1^em2Dcfaj/Cabin1^em2Dcfaj C57BL/6J-Cabin1^em2Dcfaj	cytokine storm	J:378928
	decreased spleen germinal center number	J:378928
	decreased spleen germinal center size	J:378928
	normal immune system phenotype	J:378928
	increased circulating CCL2 level	J:378928
	increased circulating chemokine level	J:378928
	increased circulating interleukin-6 level	J:378928
	increased susceptibility to Riboviria infection induced morbidity/mortality	J:378928
	normal mortality/aging	J:378928
Cabin1^tm1.1Che/Cabin1^tm1.1Che involves: 129S4/SvJae * BALB/c	abnormal cytokine secretion	J:72760
	abnormal humoral immune response	J:72760
	normal immune system phenotype	J:72760
	increased IgE level	J:72760
	increased IgG1 level	J:72760
	increased IgG2b level	J:72760
Cabin1^tm1Che/Cabin1^tm1Che involves: 129S4/SvJae	embryonic lethality during organogenesis, complete penetrance	J:72760

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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