Dach1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dach1
dachshund family transcription factor 1
MGI:1277991

15 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dach1^{tm1b(KOMP)Wtsi}/Dach1⁺ B6N(Cg)-Dach1^{tm1b(KOMP)Wtsi}/J	increased circulating alanine transaminase level	J:211773
	increased circulating chloride level	J:211773
	increased startle reflex	J:211773
Dach1^{tm1b(KOMP)Wtsi}/Dach1^{tm1b(KOMP)Wtsi} B6N(Cg)-Dach1^{tm1b(KOMP)Wtsi}/J	preweaning lethality, complete penetrance	J:211773
Dach1^tm1Krs/Dach1^tm1Krs involves: 129P2/OlaHsd	absent gastric milk in neonates	J:81143
	cyanosis	J:81143
	decreased pancreatic alpha cell number	J:166952
	decreased pancreatic beta cell number	J:166952
	decreased pancreatic beta cell proliferation	J:166952
	normal endocrine/exocrine gland phenotype	J:166952
	neonatal lethality, complete penetrance	J:81143
	normal nervous system phenotype	J:81143
	respiratory distress	J:81143
	small pancreatic islets	J:166952
Dach1^tm1Mrd/Dach1^tm1Mrd involves: 129S7/SvEvBrd	abnormal suckling behavior	J:67361
	cyanosis	J:67361
	neonatal lethality, complete penetrance	J:67361
	respiratory distress	J:67361
Dach1^tm1Mrd/Dach1^tm1Mrd involves: 129S7/SvEvBrd * C57BL/6	abnormal suckling behavior	J:67361
	cyanosis	J:67361
	neonatal lethality, complete penetrance	J:67361
	respiratory distress	J:67361

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23