Prep Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prep
prolyl endopeptidase
MGI:1270863

19 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prep^{Gt(RRM213)Byg}/Prep⁺ B6.129P2-Prep^{Gt(RRM213)Byg}	increased body mass index	J:151643
	increased body weight	J:151643
	increased kidney weight	J:151643
	increased liver weight	J:151643
	increased percent body fat/body weight	J:151643
	increased spleen weight	J:151643
Prep^{Gt(RRM213)Byg}/Prep⁺ involves: 129P2/OlaHsd * C57BL/6	decreased total body fat amount	J:151643
Prep^{Gt(RRM213)Byg}/Prep⁺ involves: 129P2/OlaHsd * C57BL/6	increased body weight	J:151643
Prep^{Gt(RRM213)Byg}/Prep^{Gt(RRM213)Byg} involves: 129P2/OlaHsd * C57BL/6	decreased body mass index	J:151643
	decreased body weight	J:151643
	decreased kidney weight	J:151643
	increased circulating leptin level	J:151643
Prep^{tm1b(KOMP)Wtsi}/Prep⁺ C57BL/6N-Prep^{tm1b(KOMP)Wtsi}/J	decreased circulating free fatty acids level	J:211773
	decreased thigmotaxis	J:211773
	increased circulating potassium level	J:211773
	increased circulating sodium level	J:211773
Prep^{tm1b(KOMP)Wtsi}/Prep^{tm1b(KOMP)Wtsi} C57BL/6N-Prep^{tm1b(KOMP)Wtsi}/J	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Prep^tm1Dgen/Prep^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	decreased prepulse inhibition	J:82809
Prep^tm1Dgen/Prep^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	increased startle reflex	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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