About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc18a3
solute carrier family 18 (vesicular monoamine), member 3
MGI:1101061
24 phenotypes from 4 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Chat/Slc18a3tm1.1Vpra/Slc18a3+
involves: 129S4/SvJae * C57BL/6J 		abnormal miniature endplate potential J:171696
normal behavior/neurological phenotype J:171696
increased acetylcholine level J:153908
Chat/Slc18a3tm1.1Vpra/Chat/Slc18a3tm1.1Vpra
involves: 129S4/SvJae * C57BL/6J 		abnormal miniature endplate potential J:153908
abnormal motor neuron innervation pattern J:153908
abnormal neuromuscular synapse morphology J:153908
abnormal skeletal muscle morphology J:153908
abnormal synaptic acetylcholine release J:153908
cyanosis J:153908
hypotonia J:153908
increased acetylcholine level J:153908
increased motor neuron number J:153908
kyphosis J:153908
neonatal lethality, complete penetrance J:153908
skeletal muscle atrophy J:153908
skeletal muscle fiber atrophy J:153908
Chat/Slc18a3tm1.1Vpra/Chat/Slc18a3tm1.1Vpra
Tg(Chat-COP4*H134R/EYFP,Slc18a3)6Gfng/0
involves: 129S4/SvJae * C57BL/6 * CBA 		normal mortality/aging J:197166
Chat/Slc18a3tm1.2Vpra/Chat/Slc18a3tm1.2Vpra
involves: 129S4/SvJae * C57BL/6J 		normal behavior/neurological phenotype J:171696
Chat/Slc18a3tm1Vpra/Chat/Slc18a3tm1.1Vpra
involves: 129S4/SvJae * C57BL/6J 		abnormal miniature endplate potential J:171696
normal behavior/neurological phenotype J:171696
hyperactivity J:171696
increased vertical activity J:171696
Chat/Slc18a3tm1Vpra/Chat/Slc18a3tm1Vpra
involves: 129S4/SvJae * C57BL/6J 		abnormal miniature endplate potential J:171696
normal behavior/neurological phenotype J:171696
hyperactivity J:171696
Slc18a3tm1Mca/Slc18a3+
involves: 129S4/SvJae * C57BL/6J 		abnormal miniature endplate potential J:137284
abnormal object recognition memory J:137284
abnormal social investigation J:137284
abnormal synaptic acetylcholine release J:137284
normal behavior/neurological phenotype J:137284
impaired coordination J:137284
Slc18a3tm1Mca/Slc18a3tm1Mca
involves: 129S4/SvJae * C57BL/6J 		abnormal endplate potential J:137284
abnormal miniature endplate potential J:137284
abnormal social investigation J:137284
abnormal synaptic acetylcholine release J:137284
decreased grip strength J:137284
impaired coordination J:137284
impaired exercise endurance J:137284
increased susceptibility to pharmacologically induced seizures J:136620
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory