Rhpn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rhpn1
rhophilin, Rho GTPase binding protein 1
MGI:1098783

24 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rhpn1^{tm1b(KOMP)Wtsi}/Rhpn1^{tm1b(KOMP)Wtsi} C57BL/6N-Rhpn1^{tm1b(KOMP)Wtsi}/Ucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hemoglobin content	J:211773
	enlarged heart	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased heart weight	J:211773
	increased liver weight	J:211773
	increased mean platelet volume	J:211773
Rhpn1^tm1Ktry/Rhpn1^tm1Ktry B6.129X1-Rhpn1^tm1Ktry	albuminuria	J:276466
Rhpn1^tm1Ktry/Rhpn1^tm1Ktry involves: 129X1/SvJ * C57BL/6	abnormal glomerular mesangium morphology	J:276466
	abnormal podocyte foot process morphology	J:276466
	abnormal podocyte morphology	J:276466
	abnormal podocyte slit diaphragm morphology	J:276466
	abnormal renal glomerulus morphology	J:276466
	albuminuria	J:276466
	enlarged kidney	J:276466
	glomerulosclerosis	J:276466
	increased renal glomerulus basement membrane thickness	J:276466
	podocyte foot process effacement	J:276466
	podocyte microvillus transformation	J:276466
	renal cast	J:276466
	renal glomerular synechia	J:276466

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23