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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Irf4
interferon regulatory factor 4
MGI:1096873
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col1a1tm1(tetO-Irf4)Sing/Col1a1tm1(tetO-Irf4)Sing
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Irf4tm1Mak/Irf4+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal class switch recombination J:203903
abnormal plasma cell differentiation J:203903
Col1a1tm1(tetO-Irf4)Sing/Col1a1tm1(tetO-Irf4)Sing
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Irf4tm1Mak/Irf4tm1Mak
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal class switch recombination J:203903
abnormal plasma cell differentiation J:203903
Irf8tm1Hor/Irf8tm1Hor
Irf4tm1Mak/Irf4tm1Mak
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell differentiation J:84577
abnormal pre-B cell morphology J:84577
absent B cells J:84577
arrested B cell differentiation J:84577
decreased dendritic cell number J:97716
decreased IgM level J:84577
decreased lymphocyte cell number J:84577
decreased plasmacytoid dendritic cell number J:97716
decreased T cell number J:84577
increased pre-B cell number J:84577
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory