E2f3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

E2f3
E2F transcription factor 3
MGI:1096340

33 phenotypes from 6 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
E2f3^tm1.1Gle/E2f3^tm1.1Gle 129-E2f3^tm1.1Gle	embryonic lethality, complete penetrance	J:138289
E2f3^tm1.1Gle/E2f3^tm1.1Gle B6.129P2-E2f3^tm1.1Gle	embryonic lethality, complete penetrance	J:138289
E2f3^tm1.1Gle/E2f3^tm1.1Gle FVB.129P2-E2f3^tm1.1Gle	embryonic lethality, complete penetrance	J:138289
E2f3^tm1.1Gle/E2f3^tm1.1Gle involves: 129P2/OlaHsd * C57BL/6J	normal mortality/aging	J:138289
E2f3^tm1.1Gle/E2f3^tm1.1Gle involves: 129P2/OlaHsd * C57BL/6J * FVB	normal mortality/aging	J:138289
E2f3^tm1.1Gle/E2f3^tm1.1Gle involves: 129P2/OlaHsd * FVB	normal mortality/aging	J:138289
E2f3^tm1.2Gle/E2f3^tm1.2Gle involves: 129P2/OlaHsd * C57BL/6	abnormal cell physiology	J:75726
	prenatal lethality, incomplete penetrance	J:75726
E2f3^{tm1b(KOMP)Wtsi}/E2f3⁺ C57BL/6N-E2f3^{tm1b(KOMP)Wtsi}/Kmpc	abnormal cornea morphology	J:211773
	abnormal jejunum morphology	J:211773
	abnormal snout morphology	J:211773
	corneal opacity	J:211773
	corneal vascularization	J:211773
	impaired glucose tolerance	J:211773
	increased lean body mass	J:211773
	increased startle reflex	J:211773
	increased total body fat amount	J:211773
	no spontaneous movement	J:211773
E2f3^{tm1b(KOMP)Wtsi}/E2f3^{tm1b(KOMP)Wtsi} C57BL/6N-E2f3^{tm1b(KOMP)Wtsi}/Kmpc	abnormal embryo size	J:211773
	no spontaneous movement	J:211773
	preweaning lethality, complete penetrance	J:211773
E2f3^tm1Lees/E2f3⁺ involves: 129S2/SvPas * C57BL/6	abnormal cell physiology	J:65128
E2f3^tm1Lees/E2f3^tm1Lees involves: 129S2/SvPas	lethality throughout fetal growth and development, complete penetrance	J:75765
E2f3^tm1Lees/E2f3^tm1Lees involves: 129S2/SvPas * C57BL/6	abnormal atrial thrombosis	J:75765
	abnormal cardiac thrombosis	J:75765
	abnormal cell cycle	J:65128
	abnormal cell physiology	J:65128
	congestive heart failure	J:75765
	decreased cell proliferation	J:65128
	decreased fetal weight	J:75765
	embryonic lethality during organogenesis, incomplete penetrance	J:75765
	lung inflammation	J:75765
	pleural effusion	J:75765
	postnatal lethality, incomplete penetrance	J:65128, J:75765
	premature death	J:75765
	pulmonary edema	J:75765
	respiratory distress	J:75765
	ruffled hair	J:75765
	slow postnatal weight gain	J:75765
E2f3^tm2.1Gle/E2f3^tm2.1Gle FVB.129S6-E2f3^tm2.1Gle	normal mortality/aging	J:138289
E2f3^tm2.1Gle/E2f3^tm2.1Gle involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	decreased white adipose tissue amount	J:138289
E2f3^tm3.1Gle/E2f3^tm3.1Gle FVB.129S6-E2f3^tm3.1Gle	normal mortality/aging	J:138289

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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